Citronellal Attenuates Oxidative Stress-Induced Mitochondrial Damage through TRPM2/NHE1 Pathway and Effectively Inhibits Endothelial Dysfunction in Type 2 Diabetes Mellitus

• Main Authors: Ya-Ling Yin (Author), Huan-Huan Wang (Author), Zi-Chen Gui (Author), Shan Mi (Author), Shuang Guo (Author), Yue Wang (Author), Qian-Qian Wang (Author), Rui-Zhu Yue (Author), Lai-Biao Lin (Author), Jia-Xin Fan (Author), Xue Zhang (Author), Bing-Yan Mao (Author), Tian-Heng Liu (Author), Guang-Rui Wan (Author), He-Qin Zhan (Author), Mo-Li Zhu (Author), Lin-Hua Jiang (Author), Peng Li (Author)
• Format: Book
• Published: MDPI AG, 2022-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

In type 2 diabetes mellitus (T2DM), oxidative stress induces endothelial dysfunction (ED), which is closely related to the formation of atherosclerosis. However, there are few effective drugs to prevent and cure it. Citronellal (CT) is an aromatic active substance extracted from citronella plants. R...