PREPERATION AND CHARACTERIZATION OF β-CYCLODEXTRIN INCLUSION COMPLEXES ORAL TABLETS CONTAINING POORLY WATER SOLUBLE GLIMIPIRIDE USING FREEZE DRYING METHOD

• Главные авторы: Yandi Syukri* (Автор), Laryssa Fernenda (Автор), issy Rizki Utami (Автор), Isna Qiftayati (Автор), Aris Perdana Kusuma (Автор), Rochmy Istikaharah (Автор)
• Формат: ‌
• Опубликовано: Universitas Gadjah Mada, 2015-05-01T00:00:00Z.
• Предметы: article
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limepiride is an oral antidiabetic drugs which is practically insoluble in water. The formation of β-cyclodextrin inclusion complex was able to increase the solubility of glimepiride. This study aim to prepare, characterize and formulation of inclusion complex tablets in order to meet the requiremen...