FOXC2 expression and epithelial-mesenchymal phenotypes are associated with castration resistance, metastasis and survival in prostate cancer

• Główni autorzy: Astrid Børretzen (Autor), Karsten Gravdal (Autor), Svein A Haukaas (Autor), Christian Beisland (Autor), Lars A Akslen (Autor), Ole J Halvorsen (Autor)
• Format: Książka
• Wydane: Wiley, 2019-10-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

Abstract Epithelial-mesenchymal transition (EMT) is important for tumour cell invasion and metastasis and is a feature of aggressive carcinomas. EMT is characterised by reduced E‐cadherin and increased N‐cadherin expression (EN‐switch), and increased expression of the EMT‐regulating transcription fa...