miR-301a Suppression within Fibroblasts Limits the Progression of Fibrosis through the TSC1/mTOR Pathway

• Main Authors: Jiexuan Wang (Author), Xun Li (Author), Mingtian Zhong (Author), Yansheng Wang (Author), Liming Zou (Author), Miaomiao Wang (Author), Xiaoli Gong (Author), Xinjie Wang (Author), Chengzhi Zhou (Author), Xiaodong Ma (Author), Ming Liu (Author)
• Format: Book
• Published: Elsevier, 2020-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Pulmonary fibrosis has been characterized by abnormal proliferation of fibroblasts and massive deposition of the extracellular matrix, which results from a complex interplay of chronic injury and inflammatory responses. MicroRNA-301a (miR-301a) is activated by multiple inflammatory stimulators, cont...