Rational Design, Synthesis and Biological Evaluation of Novel Pyrazoline-Based Antiproliferative Agents in MCF-7 Cancer Cells

• Main Authors: Mariam M. Fakhry (Author), Kazem Mahmoud (Author), Mohamed S. Nafie (Author), Ahmad O. Noor (Author), Rawan H. Hareeri (Author), Ismail Salama (Author), Safaa M. Kishk (Author)
• Format: Book
• Published: MDPI AG, 2022-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Breast cancer is a disease in which cells in the breast divide continuously without control. There are great limitations in cancer chemotherapy. Hence, it is essential to search for new cancer therapeutics. Herein, a novel series of EGFR/HER2 dual inhibitors has been designed based on the hybridizat...