Harnessing Redox Disruption to Treat Human Herpesvirus 8 (HHV-8) Related Malignancies

• Main Authors: Adélie Gothland (Author), Aude Jary (Author), Philippe Grange (Author), Valentin Leducq (Author), Laurianne Beauvais-Remigereau (Author), Nicolas Dupin (Author), Anne-Geneviève Marcelin (Author), Vincent Calvez (Author)
• Format: Book
• Published: MDPI AG, 2022-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Reprogrammed metabolism is regarded as a hallmark of cancer and offers a selective advantage to tumor cells during carcinogenesis. The redox equilibrium is necessary for growth, spread and the antioxidant pathways are boosted following Reactive Oxygen Species (ROS) production to prevent cell damage...