Knockdown resistance mutations predict DDT resistance and pyrethroid tolerance in the visceral leishmaniasis vector Phlebotomus argentipes.

• Main Authors: Bruno Gomes (Author), Bidyut Purkait (Author), Rinki Michelle Deb (Author), Aarti Rama (Author), Rudra Pratap Singh (Author), Geraldine Marie Foster (Author), Michael Coleman (Author), Vijay Kumar (Author), Mark Paine (Author), Pradeep Das (Author), David Weetman (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2017-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BACKGROUND:Indoor residual spraying (IRS) with DDT has been the primary strategy for control of the visceral leishmaniasis (VL) vector Phlebotomus argentipes in India but efficacy may be compromised by resistance. Synthetic pyrethroids are now being introduced for IRS, but with a shared target site,...