Functional assays to screen and select monoclonal antibodies that target Yersinia pestis

• Main Authors: Sergei S. Biryukov (Author), Nathaniel O. Rill (Author), Christopher P. Klimko (Author), Jennifer L. Dankmeyer (Author), Jennifer L. Shoe (Author), Melissa Hunter (Author), Yuli Talyansky (Author), Derrick Hau (Author), Marcellene A. Gates-Hollingsworth (Author), Sujata G. Pandit (Author), David P. Fetterer (Author), Ju Qiu (Author), Michael L. Davies (Author), David P. AuCoin (Author), Christopher K. Cote (Author)
• Format: Book
• Published: Taylor & Francis Group, 2023-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Yersinia pestis is a gram-negative bacterium that causes plague in animals and humans. Depending on the route of disease transmission, the bacterium can cause an acute, often fatal disease that has a narrow window for treatment with antibiotics. Additionally, antibiotic resistant strains have been i...