Gonadotropin elevation is ootoxic to ovulatory oocytes and inhibits oocyte maturation, and activin decoy receptor ActRIIB:Fc therapeutically restores maturation

• Autors principals: Lori R. Bernstein (Autor), Amelia C. L. Mackenzie (Autor), Charles L. Chaffin (Autor), Se-Jin Lee (Autor), Duane C. Kraemer (Autor), Istvan Merchenthaler (Autor)
• Format: Llibre
• Publicat: BMC, 2024-05-01T00:00:00Z.
• Matèries: article
• Accés en línia: Connect to this object online.

Abstract Background Elevated FSH often occurs in women of advanced maternal age (AMA, age ≥ 35) and in infertility patients undergoing controlled ovarian stimulation (COS). There is controversy on whether high endogenous FSH contributes to infertility and whether high exogenous FSH adversely impacts...