Analysis of epitopes on dengue virus envelope protein recognized by monoclonal antibodies and polyclonal human sera by a high throughput assay.

• Váldodahkkit: Hong-En Lin (Dahkki), Wen-Yang Tsai (Dahkki), I-Ju Liu (Dahkki), Pi-Chun Li (Dahkki), Mei-Ying Liao (Dahkki), Jih-Jin Tsai (Dahkki), Yi-Chieh Wu (Dahkki), Chih-Yun Lai (Dahkki), Chih-Hsuan Lu (Dahkki), Jyh-Hsiung Huang (Dahkki), Gwong-Jen Chang (Dahkki), Han-Chung Wu (Dahkki), Wei-Kung Wang (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: Public Library of Science (PLoS), 2012-01-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

BACKGROUND: The envelope (E) protein of dengue virus (DENV) is the major target of neutralizing antibodies and vaccine development. While previous studies on domain III or domain I/II alone have reported several epitopes of monoclonal antibodies (mAbs) against DENV E protein, the possibility of inte...