Cardamonin Reduces Acetaminophen-Induced Acute Liver Injury in Mice via Activating Autophagy and NFE2L2 Signaling

• Main Authors: Qiushi Xu (Author), Yunhui Fan (Author), Juan J. Loor (Author), Yusheng Liang (Author), Xudong Sun (Author), Hongdou Jia (Author), Chenxu Zhao (Author), Chuang Xu (Author)
• Format: Book
• Published: Frontiers Media S.A., 2020-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Cardamonin (CD), a naturally occurring chalcone derived from the Alpinia species, has been shown to exert antioxidant and anti-inflammatory activity, but its role in the prevention of acetaminophen- (APAP-) induced hepatotoxicity remains elusive. The objective of this study was to determine the prot...