Nanofibrous Scaffolds Support a 3D in vitro Permeability Model of the Human Intestinal Epithelium

• Main Authors: Jamie D. Patient (Author), Hadi Hajiali (Author), Kate Harris (Author), Bertil Abrahamsson (Author), Christer Tannergren (Author), Lisa J. White (Author), Amir M. Ghaemmaghami (Author), Philip M. Williams (Author), Clive J. Roberts (Author), Felicity R. A. J. Rose (Author)
• Format: Book
• Published: Frontiers Media S.A., 2019-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Advances in drug research not only depend on high throughput screening to evaluate large numbers of lead compounds but also on the development of in vitro models which can simulate human tissues in terms of drug permeability and functions. Potential failures, such as poor permeability or interaction...