Nanofibrous Scaffolds Support a 3D in vitro Permeability Model of the Human Intestinal Epithelium

• Главные авторы: Jamie D. Patient (Автор), Hadi Hajiali (Автор), Kate Harris (Автор), Bertil Abrahamsson (Автор), Christer Tannergren (Автор), Lisa J. White (Автор), Amir M. Ghaemmaghami (Автор), Philip M. Williams (Автор), Clive J. Roberts (Автор), Felicity R. A. J. Rose (Автор)
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• Опубликовано: Frontiers Media S.A., 2019-05-01T00:00:00Z.
• Предметы: article
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Advances in drug research not only depend on high throughput screening to evaluate large numbers of lead compounds but also on the development of in vitro models which can simulate human tissues in terms of drug permeability and functions. Potential failures, such as poor permeability or interaction...