Recent advances of NFATc1 in rheumatoid arthritis-related bone destruction: mechanisms and potential therapeutic targets

• Main Authors: Hao Zheng (Author), Yuexuan Liu (Author), Yasi Deng (Author), Yunzhe Li (Author), Shiqi Liu (Author), Yong Yang (Author), Yun Qiu (Author), Bin Li (Author), Wenbing Sheng (Author), Jinzhi Liu (Author), Caiyun Peng (Author), Wei Wang (Author), Huanghe Yu (Author)
• Format: Book
• Published: BMC, 2024-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Rheumatoid arthritis (RA) is a chronic autoimmune inflammatory disease characterized by inflammation of the synovial tissue and joint bone destruction, often leading to significant disability. The main pathological manifestation of joint deformity in RA patients is bone destruction, which o...