Generation of Otic Lineages from Integration-Free Human-Induced Pluripotent Stem Cells Reprogrammed by mRNAs

• Hoofdauteurs: Sarah L. Boddy (Auteur), Ricardo Romero-Guevara (Auteur), Ae-Ri Ji (Auteur), Christian Unger (Auteur), Laura Corns (Auteur), Walter Marcotti (Auteur), Marcelo N. Rivolta (Auteur)
• Formaat: Boek
• Gepubliceerd in: Hindawi Limited, 2020-01-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Damage to the sensory hair cells and the spiral ganglion neurons of the cochlea leads to deafness. Induced pluripotent stem cells (iPSCs) are a promising tool to regenerate the cells in the inner ear that have been affected by pathology or have been lost. To facilitate the clinical application of iP...