Generation of Otic Lineages from Integration-Free Human-Induced Pluripotent Stem Cells Reprogrammed by mRNAs

• Hlavní autoři: Sarah L. Boddy (Autor), Ricardo Romero-Guevara (Autor), Ae-Ri Ji (Autor), Christian Unger (Autor), Laura Corns (Autor), Walter Marcotti (Autor), Marcelo N. Rivolta (Autor)
• Médium: Kniha
• Vydáno: Hindawi Limited, 2020-01-01T00:00:00Z.
• Témata: article
• On-line přístup: Connect to this object online.

Damage to the sensory hair cells and the spiral ganglion neurons of the cochlea leads to deafness. Induced pluripotent stem cells (iPSCs) are a promising tool to regenerate the cells in the inner ear that have been affected by pathology or have been lost. To facilitate the clinical application of iP...