Generation of Otic Lineages from Integration-Free Human-Induced Pluripotent Stem Cells Reprogrammed by mRNAs

• Main Authors: Sarah L. Boddy (Author), Ricardo Romero-Guevara (Author), Ae-Ri Ji (Author), Christian Unger (Author), Laura Corns (Author), Walter Marcotti (Author), Marcelo N. Rivolta (Author)
• Format: Book
• Published: Hindawi Limited, 2020-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Damage to the sensory hair cells and the spiral ganglion neurons of the cochlea leads to deafness. Induced pluripotent stem cells (iPSCs) are a promising tool to regenerate the cells in the inner ear that have been affected by pathology or have been lost. To facilitate the clinical application of iP...