Cocoa Shell Extract Reduces Blood Pressure in Aged Hypertensive Rats via the Cardiovascular Upregulation of Endothelial Nitric Oxide Synthase and Nuclear Factor (Erythroid-Derived 2)-like 2 Protein Expression

Cocoa Shell Extract Reduces Blood Pressure in Aged Hypertensive Rats via the Cardiovascular Upregulation of Endothelial Nitric Oxide Synthase and Nuclear Factor (Erythroid-Derived 2)-like 2 Protein Expression

Cocoa shell is a by-product of cocoa manufacturing. We obtained an aqueous extract (CSE) rich in polyphenols and methylxanthines with antioxidant and vasodilatory properties. We aimed to evaluate the effects of CSE supplementation in aged hypertensive rats on blood pressure and the mechanism implica...

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Main Authors: Santiago Ruvira (Author), Pilar Rodríguez-Rodríguez (Author), David Ramiro-Cortijo (Author), María Martín-Trueba (Author), María A. Martín-Cabrejas (Author), Silvia M. Arribas (Author)
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Published: MDPI AG, 2023-08-01T00:00:00Z.
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