miR-214 Attenuates Aortic Valve Calcification by Regulating Osteogenic Differentiation of Valvular Interstitial Cells

• Main Authors: Ning Li (Author), Yifan Bai (Author), Guangwei Zhou (Author), Ye Ma (Author), Mengwei Tan (Author), Fan Qiao (Author), Xin Li (Author), Ming Shen (Author), Xiaowei Song (Author), Xianxian Zhao (Author), Xiaohong Liu (Author), Zhiyun Xu (Author)
• Format: Book
• Published: Elsevier, 2020-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Calcific aortic valve disease (CAVD) is a common heart valve disease in aging populations, and aberrant osteogenic differentiation of valvular interstitial cells (VICs) plays a critical role in the pathogenesis of ectopic ossification of the aortic valve. miR-214 has been validated to be involved in...