Effect of Diphenyleneiodonium Chloride on Intracellular Reactive Oxygen Species Metabolism with Emphasis on NADPH Oxidase and Mitochondria in Two Therapeutically Relevant Human Cell Types

• Main Authors: Sergejs Zavadskis (Author), Adelheid Weidinger (Author), Dominik Hanetseder (Author), Asmita Banerjee (Author), Cornelia Schneider (Author), Susanne Wolbank (Author), Darja Marolt Presen (Author), Andrey V. Kozlov (Author)
• Format: Book
• Published: MDPI AG, 2020-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Reactive oxygen species (ROS) have recently been recognized as important signal transducers, particularly regulating proliferation and differentiation of cells. Diphenyleneiodonium (DPI) is known as an inhibitor of the nicotinamide adenine dinucleotide phosphate oxidase (NOX) and is also affecting m...