Construction of a recombinant vaccine expressing Nipah virus glycoprotein using the replicative and highly attenuated vaccinia virus strain LC16m8.

• Main Authors: Shumpei Watanabe (Author), Tomoki Yoshikawa (Author), Yoshihiro Kaku (Author), Takeshi Kurosu (Author), Shuetsu Fukushi (Author), Satoko Sugimoto (Author), Yuki Nishisaka (Author), Hikaru Fuji (Author), Glenn Marsh (Author), Ken Maeda (Author), Hideki Ebihara (Author), Shigeru Morikawa (Author), Masayuki Shimojima (Author), Masayuki Saijo (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2023-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Nipah virus (NiV) is a highly pathogenic zoonotic virus that causes severe encephalitis and respiratory diseases and has a high mortality rate in humans (>40%). Epidemiological studies on various fruit bat species, which are natural reservoirs of the virus, have shown that NiV is widely distribut...