Immune checkpoint inhibitors and prostate cancer: a new frontier?

• Main Authors: Alessandra Modena (Author), Chiara Ciccarese (Author), Roberto Iacovelli (Author), Matteo Brunelli (Author), Rodolfo Montironi (Author), Michelangelo Fiorentino (Author), Giampaolo Tortora (Author), Francesco Massari (Author)
• Format: Bog
• Udgivet: Frontiers Media S.A., 2016-04-01T00:00:00Z.
• Fag: article
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Despite recent advances in the treatment of metastatic castrationresistant prostate cancer (mCRPC), agents that provide durable disease control and long-term survival are still needed. It is a fact that a tumor-induced immunosuppressive status (mediated by aberrant activation of inhibitory immune ch...