Targeting the untargetable KRAS in cancer therapy
RAS is one of the most well-known proto-oncogenes. Its gain-of-function mutations occur in approximately 30% of all human cancers. As the most frequently mutated RAS isoform, KRAS is intensively studied in the past years. Despite its well-recognized importance in cancer malignancy, continuous effort...
Saved in:
Main Authors: | Pingyu Liu (Author), Yijun Wang (Author), Xin Li (Author) |
---|---|
Format: | Book |
Published: |
Elsevier,
2019-09-01T00:00:00Z.
|
Subjects: | |
Online Access: | Connect to this object online. |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Targeting mutated KRAS in the first‐line therapy
by: Hideaki Ijichi
Published: (2024) -
Concurrent Targeting of KRAS and AKT by MiR-4689 Is a Novel Treatment Against Mutant KRAS Colorectal Cancer
by: Masayuki Hiraki, et al.
Published: (2015) -
Targeting KRAS in Solid Tumors: Current Challenges and Future Opportunities of Novel KRAS Inhibitors
by: Alice Indini, et al.
Published: (2021) -
Targeting metabolic vulnerability in mitochondria conquers MEK inhibitor resistance in KRAS-mutant lung cancer
by: Juanjuan Feng, et al.
Published: (2023) -
Integrating Targeted and Untargeted Metabolomics to Investigate the Processing Chemistry of Polygoni Multiflori Radix
by: Li Liang, et al.
Published: (2018)