Frequency of Pfcrt T76 and Pfdhfr Asn-108 Drug Resistance Mutations in falciparum Malaria in Southeastern Malaria Endemic Area of Iran

Background: Point mutations in the genes, Pfcrt and Pfdhfr, have been identified elsewhere as strongly associated with re­sistance to chloroquine (CQ) and pyrimethamine, respectively.  Methods: Using a restriction digestion method, we report the frequency of two important mutations, T76 and Asn108,...

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Main Authors: MR Razavi (Author), SR Naddaf (Author), JLe Bras (Author), A Raesi (Author), AR Esmaeili (Author), M Assmar (Author)
Format: Book
Published: Tehran University of Medical Sciences, 2008-03-01T00:00:00Z.
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