Frequency of Pfcrt T76 and Pfdhfr Asn-108 Drug Resistance Mutations in falciparum Malaria in Southeastern Malaria Endemic Area of Iran
Background: Point mutations in the genes, Pfcrt and Pfdhfr, have been identified elsewhere as strongly associated with resistance to chloroquine (CQ) and pyrimethamine, respectively. Methods: Using a restriction digestion method, we report the frequency of two important mutations, T76 and Asn108,...
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Tehran University of Medical Sciences,
2008-03-01T00:00:00Z.
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