In Vitro Inhibition of Neutrophil Elastase Activity by Inhaled Anti-Pseudomonas Antibiotics Used in Cystic Fibrosis Patients

• मुख्य लेखकों: Andreas Hector (लेखक), Matthias Kappler (लेखक), Matthias Griese (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Hindawi Limited, 2010-01-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Background. Inhaled antibiotics are commonly used in the treatment of cystic fibrosis lung disease. A previous study suggested neutrophil elastase activation by colistin in vitro. Here, we investigated direct effects of the commonly used antibiotics colistin and tobramycin on neutrophil elastase act...