Granulocyte Macrophage-Colony Stimulating Factor (GM-CSF) Downregulates the Expression of Protumor Factors Cyclooxygenase-2 and Inducible Nitric Oxide Synthase in a GM-CSF Receptor-Independent Manner in Cervical Cancer Cells

• Päätekijät: Nanyan Jiang (Tekijä), Zhiqiang Tian (Tekijä), Jun Tang (Tekijä), Rongying Ou (Tekijä), Yunsheng Xu (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: Hindawi Limited, 2015-01-01T00:00:00Z.
• Aiheet: article
• Linkit: Connect to this object online.

Enhanced expression of cyclooxygenase-2 (COX-2) and inducible nitric oxide synthase (iNOS) is associated with the pathogenic processes of various tumor types. COX-2 and iNOS expression in the immunomodulatory dendritic cells is mediated by the granulocyte macrophage-colony stimulating factor (GM-CSF...