Three intellectual disability-associated de novo mutations in MECP2 identified by trio-WES analysis

• Main Authors: Yi Gu (Author), Bingwu Xiang (Author), Lina Zhu (Author), Xiuwei Ma (Author), Xiang Chen (Author), Tao Cai (Author)
• Format: Book
• Published: BMC, 2020-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background To date, at least 746 genes have been identified to cause intellectual disability (ID). Among them, mutations in the Methyl CpG binding protein 2 (MECP2) gene are the leading cause of Rett syndrome and associated ID. Methods Considering the large number of ID-associated genes, we...