Sp1 S-Sulfhydration Induced by Hydrogen Sulfide Inhibits Inflammation via HDAC6/MyD88/NF-κB Signaling Pathway in Adjuvant-Induced Arthritis

• Main Authors: Meng Li (Author), Wei Hu (Author), Ran Wang (Author), Zhaoyi Li (Author), Yue Yu (Author), Yue Zhuo (Author), Yida Zhang (Author), Zhou Wang (Author), Yuanye Qiu (Author), Keyuan Chen (Author), Qian Ding (Author), Wei Qi (Author), Menglin Zhu (Author), Yizhun Zhu (Author)
• Format: Book
• Published: MDPI AG, 2022-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Histone deacetylase 6 (HDAC6) acts as a regulator of the nuclear factor kappa-B (NF-κB) signaling pathway by deacetylating the non-histone protein myeloid differentiation primary response 88 (MyD88) at lysine residues, which is an adapter protein for the Toll-like receptor (TLR) and interleukin (IL)...