Effects of CYP2C19 genetic polymorphisms on the cure rates of H. pylori in patients treated with the proton pump inhibitors: An updated meta-analysis

• Main Authors: Xianghong Zhao (Author), Zhongqiu Zhang (Author), Fang Lu (Author), Mengqiu Xiong (Author), Liping Jiang (Author), Ke Tang (Author), Min Fu (Author), Yu Wu (Author), Bangshun He (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: The cure rates of Helicobacter pylori (H. pylori) treatment using a proton pump inhibitor (PPI) are gradually decreasing due to antibiotic resistance, poor compliance, high gastric acidity, and cytochrome P450 2C19 (CYP2C19) polymorphism, and the effects of PPI depend on metabolic enzyme...