Ccdc103 promotes myeloid cell proliferation and migration independent of motile cilia

• Autores principales: Lauren G. Falkenberg (Autor), Sarah A. Beckman (Autor), Padmapriyadarshini Ravisankar (Autor), Tracy E. Dohn (Autor), Joshua S. Waxman (Autor)
• Formato: Libro
• Publicado: The Company of Biologists, 2021-05-01T00:00:00Z.
• Materias: article
• Acceso en línea: Connect to this object online.

The pathology of primary ciliary dyskinesia (PCD) is predominantly attributed to impairment of motile cilia. However, PCD patients also have perplexing functional defects in myeloid cells, which lack motile cilia. Here, we show that coiled-coil domain-containing protein 103 (CCDC103), one of the gen...