Protective efficacy of a Plasmodium vivax circumsporozoite protein-based vaccine in Aotus nancymaae is associated with antibodies to the repeat region.

• Asıl Yazarlar: Anjali Yadava (Yazar), Cysha E Hall (Yazar), JoAnn S Sullivan (Yazar), Douglas Nace (Yazar), Tyrone Williams (Yazar), William E Collins (Yazar), Christian F Ockenhouse (Yazar), John W Barnwell (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Public Library of Science (PLoS), 2014-10-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

We have previously reported that Vivax Malaria Protein 001 (VMP001), a vaccine candidate based on the circumsporozoite protein of Plasmodium vivax, is immunogenic in mice and rhesus monkeys in the presence of various adjuvants. In the present study, we evaluated the immunogenicity and efficacy of VM...