High Fat Diet-Induced Hepatic 18-Carbon Fatty Acids Accumulation Up-Regulates CYP2A5/CYP2A6 via NF-E2-Related Factor 2

• المؤلفون الرئيسيون: Xing-he Wang (مؤلف), Xiao-xu Cui (مؤلف), Xiao-qi Sun (مؤلف), Xing-hui Wang (مؤلف), Xiao-chong Li (مؤلف), Yue Qi (مؤلف), Wei Li (مؤلف), Mei-yu Han (مؤلف), Ishfaq Muhammad (مؤلف), Xiu-ying Zhang (مؤلف)
• التنسيق: كتاب
• منشور في: Frontiers Media S.A., 2017-05-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

To investigate the role of hepatic 18-carbon fatty acids (FA) accumulation in regulating CYP2A5/2A6 and the significance of Nrf2 in the process during hepatocytes steatosis, Nrf2-null, and wild type mice fed with high-fat diet (HFD), and Nrf2 silenced or over expressed HepG2 cells administered with...