Prevention of Stress-Induced Depressive-like Behavior by Saffron Extract Is Associated with Modulation of Kynurenine Pathway and Monoamine Neurotransmission

• Main Authors: Camille Monchaux De Oliveira (Author), Véronique De Smedt-Peyrusse (Author), Jennifer Morael (Author), Sylvie Vancassel (Author), Lucile Capuron (Author), David Gaudout (Author), Line Pourtau (Author), Nathalie Castanon (Author)
• Format: Book
• Published: MDPI AG, 2021-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Depressive disorders are a major public health concern. Despite currently available treatment options, their prevalence steadily increases, and a high rate of therapeutic failure is often reported, together with important antidepressant-related side effects. This highlights the need to improve exist...