GRAIL and Otubain-1 are Related to T Cell Hyporesponsiveness during Trypanosoma cruzi Infection.

• المؤلفون الرئيسيون: Cinthia C Stempin (مؤلف), Jorge D Rojas Marquez (مؤلف), Yamile Ana (مؤلف), Fabio M Cerban (مؤلف)
• التنسيق: كتاب
• منشور في: Public Library of Science (PLoS), 2017-01-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

BACKGROUND:Trypanosoma cruzi infection is associated with severe T cell unresponsiveness to antigens and mitogens and is characterized by decreased IL-2 synthesis. In addition, the acquisition of the anergic phenotype is correlated with upregulation of "gene related to anergy in lymphocytes&quo...