Safety and efficacy assessment of two new leprosy skin test antigens: randomized double blind clinical study.

New tools are required for the diagnosis of pre-symptomatic leprosy towards further reduction of disease burden and its associated reactions. To address this need, two new skin test antigens were developed to assess safety and efficacy in human trials.A Phase I safety trial was first conducted in a...

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Glavni autori: Becky L Rivoire (Autor), Nathan A Groathouse (Autor), Stephen TerLouw (Autor), Kapil Dev Neupane (Autor), Chaman Ranjit (Autor), Bishwa Raj Sapkota (Autor), Saraswoti Khadge (Autor), Chhatra B Kunwar (Autor), Murdo Macdonald (Autor), Rachel Hawksworth (Autor), Min B Thapa (Autor), Deanna A Hagge (Autor), Melinda Tibbals (Autor), Carol Smith (Autor), Tina Dube (Autor), Dewei She (Autor), Mark Wolff (Autor), Eric Zhou (Autor), Mamodikoe Makhene (Autor), Robin Mason (Autor), Christine Sizemore (Autor), Patrick J Brennan (Autor)
Format: Knjiga
Izdano: Public Library of Science (PLoS), 2014-01-01T00:00:00Z.
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