Widely metastatic IDH1-mutant glioblastoma with oligodendroglial features and atypical molecular findings: a case report and review of current challenges in molecular diagnostics

• Main Authors: Carlos G. Romo (Author), Doreen N. Palsgrove (Author), Ananyaa Sivakumar (Author), Christen R. Elledge (Author), Lawrence R. Kleinberg (Author), Kaisorn L. Chaichana (Author), Christopher D. Gocke (Author), Fausto J. Rodriguez (Author), Matthias Holdhoff (Author)
• Format: Book
• Published: BMC, 2019-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Gliomas with 1p/19q-codeletion as well as mutation of isocitrate dehydrogenase (IDH) 1 are typically characterized as oligodendrogliomas with comparatively good response to treatment with radiation and chemotherapy. Case presentation We present the case of a 28-year-old man with...