Chronic stress is associated with pain precipitation and elevation in DeltaFosb expression

• Main Authors: Hang eWang (Author), Xinrong eTao (Author), Si-Ting eHuang (Author), Liang eWu (Author), Hui-Li eTang (Author), Ying eSong (Author), Gongliang eZhang (Author), Yong-Mei eZhang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2016-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

A number of acute or repeated stimuli can induce expression of DeltaFosB (ΔFosB), a transcription factor derived from the fosB gene (an osteosarcoma viral oncogene) via alternative splicing. ΔFosB protein is currently viewed as a 'molecular switch' to repeated stimuli that gradually conver...