Population Pharmacokinetics of Amikacin in Patients on Veno-Arterial Extracorporeal Membrane Oxygenation

• Main Authors: Claire Pressiat (Author), Agathe Kudela (Author), Quentin De Roux (Author), Nihel Khoudour (Author), Claire Alessandri (Author), Hakim Haouache (Author), Dominique Vodovar (Author), Paul-Louis Woerther (Author), Alice Hutin (Author), Bijan Ghaleh (Author), Anne Hulin (Author), Nicolas Mongardon (Author)
• Format: Book
• Published: MDPI AG, 2022-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Veno-arterial extracorporeal membrane oxygenation (V-A ECMO) support leads to complex pharmacokinetic alterations, whereas adequate drug dosing is paramount for efficacy and absence of toxicity in critically ill patients. Amikacin is a major antibiotic used in nosocomial sepsis, especially for these...