Systematically optimized topical delivery system for Loperamide hydrochloride: Formulation design, in vitro and in vivo biopharmaceutical evaluation

• मुख्य लेखकों: Jianhui Shu (लेखक), Jingjing Zhao (लेखक), Fang Guo (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Elsevier, 2018-05-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

This study aimed to develop a suitable topical delivery system containing diethylene glycol monoethyl ether (DGME) for Loperamide hydrochloride (Lop). Two factors, three levels Central-Composite design were applied by generating a quadratic polynomial equation to form contour plots and response surf...