Pharmacokinetics of apixaban and tacrolimus or cyclosporine in kidney and lung transplant recipients

• Main Authors: Holly Mansell (Author), Ahmed Shoker (Author), Jane Alcorn (Author), Mark E. Fenton (Author), Julian S. Tam (Author), William Semchuk (Author), Babar Bashir (Author), Walter K. Kraft (Author), Shenzhen Yao (Author), James D. Douketis (Author)
• Format: Book
• Published: Wiley, 2022-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Apixaban is frequently used off‐label in transplant recipients. However, a potential drug interaction exists with the calcineurin inhibitors. We conducted an open‐label drug-drug interaction study to determine the pharmacokinetics of apixaban in lung and kidney transplant recipients who wer...