Sitagliptin alleviated myocardial remodeling of the left ventricle and improved cardiac diastolic dysfunction in diabetic rats

• Hoofdauteurs: Yu-Sheng Liu (Auteur), Zhi-Wei Huang (Auteur), Lin Wang (Auteur), Xin-Xin Liu (Auteur), Yong-Mei Wang (Auteur), Yun Zhang (Auteur), Mei Zhang (Auteur)
• Formaat: Boek
• Gepubliceerd in: Elsevier, 2015-03-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Objective: Sitagliptin, a dipeptidyl peptidase IV (DPP-Ⅳ) inhibitor, has a biological role in improving the serum levels of glucagon-like peptide 1 (GLP-1). Hence, we sought to determine the effect of sitagliptin on myocardial inflammation, collagen metabolism, lipid content and myocardial apoptosis...