Cost-effectiveness of cascade genetic testing for familial hypercholesterolemia in the United States: A simulation analysis

• Main Authors: Candace L. Jackson (Author), Todd Huschka (Author), Bijan Borah (Author), Katherine Agre (Author), Magdi Zordok (Author), Medhat Farwati (Author), James Moriarty (Author), Iftikhar J. Kullo (Author)
• Format: Book
• Published: Elsevier, 2021-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective There is no coordinated cascade testing program for familial hypercholesterolemia (FH) in the U.S. We evaluated the contemporary cost-effectiveness of cascade genetic testing relatives of FH probands with a pathogenic variant. Methods: A simulation model was created to simulate multiple fa...