Population Pharmacokinetics of Continuous-Infusion Meropenem in Febrile Neutropenic Patients with Hematologic Malignancies: Dosing Strategies for Optimizing Empirical Treatment against Enterobacterales and <i>P. aeruginosa</i>

• Главные авторы: Pier Giorgio Cojutti (Автор), Anna Candoni (Автор), Davide Lazzarotto (Автор), Carla Filì (Автор), Maria Zannier (Автор), Renato Fanin (Автор), Federico Pea (Автор)
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• Опубликовано: MDPI AG, 2020-08-01T00:00:00Z.
• Предметы: article
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A population pharmacokinetic analysis of continuous infusion (CI) meropenem was conducted in a prospective cohort of febrile neutropenic (FN) patients with hematologic malignancies. A non-parametric approach with Pmetrics was used for pharmacokinetic analysis and covariate evaluation. Monte Carlo si...