Profile of Human TERT and P73 in Oral Squamous Cell Carcinoma Cell Lines Compared to Normal Human Oral Mucosa: a Preliminary Study

• 主要な著者: Ambar Kusuma Astuti (著者), Irfan Prasetyo (著者), Justisia Nafsi Yunita (著者), Yuniardini Septorini Wimardhani (著者), Febrina Rahmayanti (著者)
• フォーマット: 図書
• 出版事項: Faculty of Dentistry, Universitas Indonesia, 2013-05-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

<p>Genetic alteration on p53 allows cellular immortalization and predisposes cells to neoplastic transformation. This immortalization is related to telomere length maintenance by telomerase. Human TERT is a key compo-nent of telomerase, which activity is suppressed by p53. The p73, the homolog...