Tuning the Anthranilamide Peptidomimetic Design to Selectively Target Planktonic Bacteria and Biofilm

• Main Authors: Rajesh Kuppusamy (Author), Muhammad Yasir (Author), Tsz Tin Yu (Author), Florida Voli (Author), Orazio Vittorio (Author), Michael J. Miller (Author), Peter Lewis (Author), David StC Black (Author), Mark Willcox (Author), Naresh Kumar (Author)
• Format: Book
• Published: MDPI AG, 2023-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

There is a pressing need to develop new antimicrobials to help combat the increase in antibiotic resistance that is occurring worldwide. In the current research, short amphiphilic antibacterial and antibiofilm agents were produced by tuning the hydrophobic and cationic groups of anthranilamide pepti...