PNA-Modified Liposomes Improve the Delivery Efficacy of CAPIRI for the Synergistic Treatment of Colorectal Cancer

• Main Authors: Wenbin Diao (Author), Ben Yang (Author), Sipeng Sun (Author), Anping Wang (Author), Rongguan Kou (Author), Qianyun Ge (Author), Mengqi Shi (Author), Bo Lian (Author), Tongyi Sun (Author), Jingliang Wu (Author), Jingkun Bai (Author), Meihua Qu (Author), Yubing Wang (Author), Wenjing Yu (Author), Zhiqin Gao (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Tumor-associated antigen mucin 1 (MUC1) is highly expressed in colorectal cancer and is positively correlated with advanced stage at diagnosis and poor patient outcomes. The combination of irinotecan and capecitabine is standard chemotherapy for metastatic colorectal cancer and is known as XELIRI or...