Adenosine monophosphate‐activated protein kinase is elevated in human cachectic muscle and prevents cancer‐induced metabolic dysfunction in mice

• Main Authors: Steffen H. Raun (Author), Mona S. Ali (Author), Xiuqing Han (Author), Carlos Henríquez‐Olguín (Author), T.C. Phung Pham (Author), Roberto Meneses‐Valdés (Author), Jonas R. Knudsen (Author), Anna C.H. Willemsen (Author), Steen Larsen (Author), Thomas E. Jensen (Author), Ramon Langen (Author), Lykke Sylow (Author)
• Format: Book
• Published: Wiley, 2023-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Metabolic dysfunction and cachexia are associated with poor cancer prognosis. With no pharmacological treatments, it is crucial to define the molecular mechanisms causing cancer‐induced metabolic dysfunction and cachexia. Adenosine monophosphate‐activated protein kinase (AMPK) co...