Suppression of Inflammatory Cardiac Cytokine Network in Rats with Untreated Obesity and Pre-Diabetes by AT2 Receptor Agonist NP-6A4

• Main Authors: Madhavi P. Gavini (Author), Abuzar Mahmood (Author), Anthony M. Belenchia (Author), Paige Beauparlant (Author), Senthil A. Kumar (Author), Sivakumar Ardhanari (Author), Vincent G. DeMarco (Author), Lakshmi Pulakat (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Obesity affects over 42% of the United States population and exacerbates heart disease, the leading cause of death in men and women. Obesity also increases pro-inflammatory cytokines that cause chronic tissue damage to vital organs. The standard-of-care does not sufficiently attenuate these inflamma...