Transcriptional profiling of paediatric ependymomas identifies prognostically significant groups

• मुख्य लेखकों: Maria Łastowska (लेखक), Ewa Matyja (लेखक), Anna Sobocińska (लेखक), Bartosz Wojtaś (लेखक), Magdalena Niemira (लेखक), Anna Szałkowska (लेखक), Adam Krętowski (लेखक), Agnieszka Karkucińska‐Więckowska (लेखक), Magdalena Kaleta (लेखक), Maria Ejmont (लेखक), Magdalena Tarasińska (लेखक), Marta Perek‐Polnik (लेखक), Bożenna Dembowska‐Bagińska (लेखक), Maciej Pronicki (लेखक), Wiesława Grajkowska (लेखक), Joanna Trubicka (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Wiley, 2021-11-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Abstract The majority of supratentorial ependymomas in children contain oncogenic fusions, such as ZFTA-RELA or YAP1‐MAMLD1. In contrast, posterior fossa (PF) ependymomas lack recurrent somatic mutations and are classified based on gene expression or methylation profiling into group A (PFA) and grou...