Platelet-Activating Factor Induces Th17 Cell Differentiation

• Main Authors: Anne-Marie Drolet (Author), Maryse Thivierge (Author), Sylvie Turcotte (Author), Dominique Hanna (Author), Bruno Maynard (Author), Jana Stankovà (Author), Marek Rola-Pleszczynski (Author)
• Format: Book
• Published: Hindawi Limited, 2011-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Th17 cells have been implicated in a number of inflammatory and autoimmune diseases. The phospholipid mediator platelet-activating factor (PAF) is found in increased concentrations in inflammatory lesions and has been shown to induce IL-6 production. We investigated whether PAF could affect the deve...