Chronic everolimus treatment of high‐fat diet mice leads to a reduction in obesity but impaired glucose tolerance

• Main Authors: Geng‐Ruei Chang (Author), Po‐Hsun Hou (Author), Chao‐Min Wang (Author), Ching‐Feng Wu (Author), Huang‐Kai Su (Author), Huei‐Jyuan Liao (Author), To‐Pang Chen (Author)
• Format: Book
• Published: Wiley, 2021-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Everolimus, which inhibits mTOR kinase activity and is clinically used in graft rejection treatment, may have a two‐sided influence on metabolic syndrome; its role in obesity and hyperglycemic in animals and humans, however, has been explored insufficiently. This study further determined ho...