Mesenchymal Stem Cells Alleviate Renal Fibrosis and Inhibit Autophagy via Exosome Transfer of miRNA-122a

• Main Authors: Dawei Li (Author), Junwen Qu (Author), Xiaodong Yuan (Author), Shaoyong Zhuang (Author), Haoyu Wu (Author), Ruoyang Chen (Author), Jiajin Wu (Author), Ming Zhang (Author), Liang Ying (Author)
• Format: Book
• Published: Hindawi Limited, 2022-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Exosomes derived from mesenchymal stem cell (MSC) alleviate kidney damage through autophagy. This study determined whether MSCs relieve renal fibrosis and inhibit autophagy by exosome transfer of miRNA-122a. The gene expression involved in the mTOR signaling pathway and autophagy was assessed in TGF...