Novel 4-benzoylpyridine oxime derivative GIZH-298 with aticonvulsant activity

• 主要な著者: L. A. Zhmurenko (著者), G. V. Mokrov (著者), L. N. Nerobkova (著者), S. A. Litvinova (著者), I. O. Gaydukov (著者), T. A. Voronina (著者), T. A. Gudasheva (著者)
• フォーマット: 図書
• 出版事項: LLC "Publisher OKI", 2017-02-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Novel derivative of benzoylpyridine oximes - GIZH-298 (4-benzoylpyridine 0-(2-morpholinoethyl) oxime oxalate) was designed and synthesized in this work. This compound has a broad spectrum of anticonvulsant effects, eliminating primary generalized seizures in maximal electroshock (MES) and corazol an...