Novel 4-benzoylpyridine oxime derivative GIZH-298 with aticonvulsant activity

• Main Authors: L. A. Zhmurenko (Author), G. V. Mokrov (Author), L. N. Nerobkova (Author), S. A. Litvinova (Author), I. O. Gaydukov (Author), T. A. Voronina (Author), T. A. Gudasheva (Author)
• Format: Book
• Published: LLC "Publisher OKI", 2017-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Novel derivative of benzoylpyridine oximes - GIZH-298 (4-benzoylpyridine 0-(2-morpholinoethyl) oxime oxalate) was designed and synthesized in this work. This compound has a broad spectrum of anticonvulsant effects, eliminating primary generalized seizures in maximal electroshock (MES) and corazol an...